Severe COVID-19 more likely in those with dementia alleles

UK Biobank study shows homozygous carriers have more than twice the risk of other common genotypes
Reuters Health Staff writer
Vial of blood for genetic testing

Homozygosity for the apolipoprotein E ε4 (ApoE ε4) genotype appears to be associated with a higher rate of COVID-19, a study shows.

UK and US researchers evaluated the association between ApoE ε4 alleles and severe COVID-19, with testing largely restricted to UK hospital inpatients with clinical signs of severe infection.