Single week of adjuvant breast radiotherapy ‘effective’

But patient selection would be important, commentators say
Clare Pain
Breast cancer radiotherapy

One week of hypofractionated radiotherapy after surgery for breast cancer is not inferior to a standard three-week schedule, according to results from a UK clinical trial.

In the FAST-Forward trial, 4096 women post-breast conserving surgery or mastectomy were randomised to standard care radiotherapy of 40Gy in 15 sessions over three weeks or to one of two hypofractionated one-week regimens of five doses totalling 27Gy and 26Gy respectively.