Skip levothyroxine in pregnant euthyroid women with thyroid antibodies

Latest research suggests existing US guidelines needs to be changed

Levothyroxine before and during pregnancy does not improve the odds of a live birth in women with normal thyroid function and thyroid peroxidase (TPO) antibodies, a study shows.

pregant woman holding her bare abdomen

The TABLET trial, conducted at 49 centres in the UK, was presented at the Endocrine Society's annual meeting in New Orleans and simultaneously published in the New England Journal of Medicine.

TPO antibodies are present in about 10% of euthyroid women and they have been linked to increased risk of