‘Steady decline’ in C-peptide starts six months before T1D diagnosis

The findings suggest an early window of opportunity for disease-modifying therapy, researchers say
Clare Pain
Vial of blood to be tested for C-peptide

A longitudinal study tracking people as they develop type 1 diabetes shows that C-peptide levels maintain a steady decline starting six months before clinical diagnosis.

The results suggest that interventions aimed at reducing damage to beta-cells might need to be carried out earlier than previously thought, the US authors say.