Stress tests 'unreliable to rule out LMCA disease'

A post-hoc analysis of the ISCHEMIA trial suggests invasive coronary angiography may be needed for certain patients

Non-invasive imaging and exercise stress tests have limited ability to predict left main coronary artery stenosis of 50% or more in patients with moderate-to-severe ischaemia, a comprehensive analysis shows.

Instead, clinicians may need to rely on anatomical imaging to rule out left main coronary artery (LMCA) disease in this setting, according to international researchers, including Adelaide cardiac imaging specialist Professor Joseph Selvanayagam from Flinders University.

In a post-hoc analysis of the