Surgery for temporal lobe epilepsy: piriform cortex matters

Removal of this part of the cortex is associated with more patients becoming seizure-free, but there may be additional surgical risks

Patients are more likely to be seizure-free after surgery for temporal lobe epilepsy if the piriform-cortex is included in the resection, researchers report.

Saggital section shwoing one half of the brain

"The piriform cortex is part of the olfactory system, and so an important signal amplifier, hugely important in animals, less so in humans," said Dr Matthias Koepp from the UK National Institute for Health Research, in London.

"Still, it looks like it is an important hub, or switch, which if removed as part of epilepsy surgery, can switch off the epilepsy