TGA warns on liver toxicity with tocilizumab

The drug has led to jaundice, hepatitis and liver failure, the watchdog says
Lydia Hales

The TGA is investigating the incidence of liver damage associated with the rheumatoid arthritis drug tocilizumab, following adverse events ranging from jaundice to acute hepatic failure.

Tocilizumab (Actemra, Roche) is known to cause transient or intermittent mild to moderate elevation of hepatic transaminases.