Tolerability of antiseizure drugs ‘not improved’ in 30 years: study

But second-generation medications at least offer more options, says a leading neurologist
Lydia Hales

The tolerability of antiseizure medications (ASMs) has not improved in the past 30 years, despite the introduction of more than a dozen second-generation drugs, researchers say.

Data on discontinuation of ASM at a single centre in Scotland across three decades shows that one in six prescribed medications was withdrawn because of adverse events (AEs), often at low doses, they said.