Topical imiquimod as good as surgery for vulvar intraepithelial neoplasia: trial

The immune response modifier can be considered first-line treatment in women likely to stick with it, doctors suggest

Topical imiquimod works just as well as surgery for the first-line treatment of vulvar high-grade squamous intraepithelial lesions, according to a phase III non-inferiority trial.

Micrograph of vulvar intraepithelial neoplasia

Results from the multicentre Austrian study also showed no significant difference in rates of HPV clearance, adverse events or treatment

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