Topical imiquimod as good as surgery for vulvar intraepithelial neoplasia: trial

The immune response modifier can be considered first-line treatment in women likely to stick with it, doctors suggest
Reuters Health
Micrograph of vulvar intraepithelial neoplasia

Topical imiquimod works just as well as surgery for the first-line treatment of vulvar high-grade squamous intraepithelial lesions, according to a phase III non-inferiority trial.

Results from the multicentre Austrian study also showed no significant difference in rates of HPV clearance, adverse events or treatment satisfaction, the researchers say.