Triple combo cream ‘tops’ for melasma

The first systematic review focusing on self-applied therapies offers guidance on the most useful agents

Triple combination cream and hydroquinone alone remain the most effective self-administered topical interventions for melasma, a new analysis confirms.

The use of broad-spectrum sunscreen was also of great importance in managing the condition, according to German clinicians, while some over-the-counter cosmetic and herbal products also showed promise.