Two stem-cell transplants better than one in neuroblastoma

The trial including Australian patients 'has changed current practice', experts say

Two autologous stem-cell transplants provide better event-free survival in patients with high-risk neuroblastoma, compared with a single stem-cell transplant, a clinical trial shows.

child with cancer in hospital with nurse

Researchers from 142 Children's Oncology Group centres in five countries, including Australia and New Zealand, investigated whether intensifying consolidation treatment with tandem transplant (two transplants, 6-10 weeks apart) could improve event-free survival compared with a single transplant.

They enrolled 355 patients