What's a safe dose of glucocorticoids in RA?
Threshold dose for increased risk of cardiac events pinpointed, researchers say
Patients with rheumatoid arthritis (RA) who initiate glucocorticoids are at increased risk of a cardiovascular event if their dose is greater than 4mg/day of prednisone, a registry study shows.
The US authors also warn that a cumulative dose of above 750mg prednisone equivalent in the preceding six months, or a cumulative dose of more than 1100mg in a year, raises cardiovascular risk.
Cumulative doses below these levels do
