Which procedure is best for removal of large sessile serrated lesions?

A new standard of care has emerged, Australian gastroenterologists say
Clare Pain
colonoscopy equipment

Piecemeal cold-snare polypectomy for removal of large sessile serrated polyps has equivalent efficacy to conventional endoscopic mucosal resection and a lower risk of adverse events, a study shows.

Australian researchers determined outcomes for 156 large (20mm or greater) sessile serrated lesions occurring in 121 patients treated by piecemeal cold-snare polypectomy at four tertiary centres between 2016 and 2020.

Technical success, defined as complete removal of all polypoid tissue, was 100%, the investigators reported in Gut.

They compared these outcomes with those for 406 lesions in a cohort of 353 patients who were treated with endoscopic mucosal resection at the same centres between 2008 and 2016.