Who should be screened for familial Paget’s disease?
The longest follow-up yet of relatives shows only a handful go on to develop the condition
![phlebologist holding a tube of blood](https://www.ausdoc.com.au/wp-content/uploads/2022/08/blood20sample20blood20test20pathology-3.jpg)
Close relatives of people with familial Paget’s disease of bone who carry mutations in the sequestosome 1 gene are probably the only people worth screening for the disease, a Dutch study suggests.
Even so, their chance of developing the condition appears to be low, the results show.