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GPs are often the first to request blood tests that reveal monoclonal gammopathy of undetermined significance (MGUS), a usually benign condition but an important precursor to multiple myeloma.

Recognising and monitoring MGUS in primary care allows close follow-up and, if progression occurs, earlier treatment with improved outcomes. In this Q&A, Dr Bryant offers practical tips for identifying and managing MGUS in routine practice.

AusDoc: Can you explain what MGUS is, how it is typically diagnosed, and how GPs can differentiate between MGUS and other similar conditions?