A GP guide to chronic kidney disease in diabetes

'Unusual' features should alert the clinician to potential alternative coexisting pathologies.

Diabetes is the most common cause of kidney failure (37% non-Indigenous Australians; 69% Indigenous Australians) and around 50% of people with type 2 diabetes (T2DM) will develop diabetic nephropathy.1,2

The natural history is initial hyperfiltration before the onset of albuminuria which progresses to overt proteinuria after which the eGFR declines.