A GP guide to preventing congenital CMV

The GP is key to current strategies for prevention of congenital CMV, which focus on education about reducing risk of transmission, targeted testing of those at risk, and prompt identification of infection.

Need to know:

Cytomegalovirus is a common herpesvirus that typically causes no symptoms or complications in healthy, immunocompetent individuals. However, if a woman acquires CMV during pregnancy, vertical transmission may occur, potentially leading to serious sequelae in the developing fetus.

These may include fetal brain damage, hydrops, anaemia, stillbirth or neonatal death. Long-term outcomes include sensorineural hearing loss, developmental delay, epilepsy and cerebral palsy.

In high-income countries, about one in 200 infants have congenital CMV,1 and around one in 10 of these will develop significant long-term health impacts.2

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