COVID-19 vaccines: An update on the safety and effectiveness data

The latest COVID-19 vaccination effectiveness and safety data from around the world have implications for Australia’s vaccine rollout

Need to know:

  • The Delta variant of SARS-CoV-2 is associated with increased transmissibility and disease severity.
  • Population-wide vaccine safety and effectiveness data are now available.
  • The Pfizer-BioNTech vaccine remains highly effective against variants of concern.
  • The AstraZeneca vaccine is highly effective against severe disease due to Alpha and Delta variants.
  • Neutralisation studies suggest the Moderna vaccine has similar efficacy to the Pfizer vaccine.
  • Preliminary data show the Novavax vaccine may also have similar efficacy to the Pfizer vaccine.
  • Thrombosis with thrombocytopenia syndrome (TTS) after AstraZeneca vaccination is a rare but significant complication in all age groups, particularly those under 60.

The COVID-19 vaccine landscape is changing every day.