A GP guide to adult adrenal insufficiency

An in-depth look at primary and secondary adrenal insufficiency, oral glucocorticoid replacement options and how to manage adrenal crisis.

Need to know:

  • Primary adrenal insufficiency (Addison’s disease) is characterised by the lifelong requirement for both glucocorticoid and mineralocorticoid therapy.
  • Secondary adrenal insufficiency is a result of impairment of the hypothalamic–pituitary–adrenal axis.