A GP guide to adult adrenal insufficiency

An in-depth look at primary and secondary adrenal insufficiency, oral glucocorticoid replacement options and how to manage adrenal crisis.

Adrenal insufficiency in adults may follow a variable clinical course, depending on the acuity of onset and associated underlying pathophysiology.

Symptoms may range from the vague, insidious, non-specific features of chronic insufficiency to the collapse of adrenal crisis.