A GP guide to adult adrenal insufficiency

An in-depth look at primary and secondary adrenal insufficiency, oral glucocorticoid replacement options and how to manage adrenal crisis.

Adrenal insufficiency in adults may follow a variable clinical course, depending on the acuity of onset and associated underlying pathophysiology.

Symptoms may range from the vague, insidious, non-specific features of chronic insufficiency to the collapse of adrenal crisis.

A high level of suspicion is required on the part of the treating clinician to identify this condition.

Patients with a diagnosis of adrenal insufficiency need ongoing support, review and education to ensure appropriate cortisol replacement in maintained in the long term and around sick days.