Clinical Focus 
 Therapy Update

A GP guide to Botox for neurological conditions

PBS listings for botulinum toxin have grown in recent years, reflecting its safety and efficacy in treating a wide variety of neurological conditions.
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19 February 2020
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The botulinum toxins, serotypes A-G, are seven neurotoxic proteins produced by bacteria of the genus clostridium.

All types disrupt neurotransmitter release by interfering with the exocytosis of vesicles from neurons.1

Botulinum toxins type A and B have been purposed for medical use in humans.

However, all PBS-subsidised products contain type A toxin: onabotulinumtoxinA (Botox), abobotulinumtoxinA (Dysport) and incobotulinumtoxinA (Xeomin).

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