A GP guide to managing Mycoplasma genitalium

Concern is rising over the increased antimicrobial resistance of this STI

The emerging sexually transmitted infection Mycoplasma genitalium has gained considerable attention in recent years due to a marked increase in antimicrobial resistance.

Mycoplasma genitalium

M. genitalium belongs to the genus Mycoplasma, which are the smallest prokaryocytes capable of self-replication.1

The organism was first isolated in 1981 during studies of non-gonococcal urethritis (NGU). It is fastidious in nature and difficult to grow in culture.

Until recently, diagnostic