Opinion: The allostatic narrative is powerful

USING anti-inflammatories to treat depression, co-occurring non-communicable diseases in individuals, stress as a trigger for diabetes, omega-3 fatty acids potentially preventing and treating heart disease, the role of physical activity in preventing the telomeres shortening — is it possible to link such disparate findings in a single narrative? 

Bruce McEwen proposed the allostatic load model 20 years ago to understand how non-communicable diseases such as diabetes, depression and stroke develop, and how they may best be treated.

Underlying the allostatic load model is