Oxytocin analogues may relieve IBS symptoms

Oxytocin has potential applications as an analgesic in patients with chronic abdominal pain conditions such irritable bowel syndrome, Queensland researchers have shown.

Analogues of the peptide hormone may become useful analgesics as the hormone acts on oxytocin receptors in the gut to mediate hypersensitivity and pain, work by Professor Paul Alewood and colleagues from the University of Queensland has shown.

As a peptide, oxytocins would be degraded in the gut but analogues have been developed that endure in the GI tract and show significant potential in alleviating abdominal pain, Professor Alewood