Two SSRIs lead to higher incident of birth defects

The SSRIs paroxetine and fluoxetine confer a small increased risk of birth defects when used in early pregnancy, but no such association is seen for other SSRIs, according to a major US study.

The “reassuring” findings shows no evidence to support previously reported associations between maternal sertraline use and birth defects, and no significant link between citalopram use and birth defects.

However, the analysis of data from 18,000 mothers of infants with birth defects found that some occurred more frequently among infants of mothers who took paroxetine or