Metastatic prostate cancer developments

THE treatment of metastatic prostate cancer has advanced significantly in recent years due to better understanding of the drivers of prostate cancer and research into the mechanisms of resistance to hormonal manipulation.

Typically, advanced prostate cancer is diagnosed in men with localised prostate cancer, where PSA levels have risen following treatment, indicating that advanced cancer has developed.

More rarely, men present with bone or abdominal pain leading to a primary diagnosis of advanced cancer, and occasionally an