Putting use of PPIs in perspective

Therapeutic Guidelines: Gastrointestinal considers that PPIs are superior to H2 antagonists in the treatment of peptic ulcers and erosive oesophagitis. PPIs can be combined with antibiotics to treat patients who are infected with Helicobacter pylori. First-line eradication therapy usually only requires the PPI to be taken for seven days.

Proton pump inhibitors are commonly prescribed for gastro-oesophageal reflux disease. Therapeutic Guidelines: Gastrointestinal recommends that the initial treatment is for one or two months.

The once-daily