HIV breakthrough galvanises scientists

US scientists say they are a step closer to finding a cure for HIV-1/Aids after they managed to almost entirely eliminate the devastating immune disease from infected mice.

Writing in Molecular Therapy, they say they have demonstrated the “feasibility and efficiency” of removing the HIV-1 provirus using a new gene-editing technique.

Significantly, the authors note that some of the mice had been “humanised” after being given some human immune cells.

In these animals, “successful proviral excision was detected … in the spleen, lungs,