Hopes of a drug to halt prostate cancer
A new treatment shows promise in halting the march of aggressive prostate cancer.
Scientists have found a novel drug target that affects the way tumours form nourishing blood vessels.
Blocking the molecule, SRPK1, stopped the progression of prostate cancer in mice.
Analysis of human prostate cancer tumour samples showed that SRPK1 increases as the cancer gets more aggressive.
The molecule plays a vital role in "angiogenesis" - the process by which tumours generate new blood vessels that feed them with nutrients.
Researchers found that drugs known as Sphinx compounds, designed to inhibit the