Progression-free survival overused for cancer drug approvals, oncologists warn
Progression-free survival is a poor surrogate for overall survival and should not be relied upon as a primary endpoint for registration and marketing of anticancer…
In-depth coverage of specialist medicine
Progression-free survival is a poor surrogate for overall survival and should not be relied upon as a primary endpoint for registration and marketing of anticancer…
One in three adults with NAFLD-related cirrhosis and diabetes in the decade up to 2018 progressed to decompensated cirrhosis, an Australian study shows. Age, hypertension and extrahepatic cancer all…
Over-80s with colorectal cancer are far less likely to receive adjuvant chemotherapy than younger patients despite having similar oncological and post-resection outcomes, Australian doctors say. Their…
Prophylactic salpingo-oophorectomy at the time of breast cancer surgery in patients with the BRCA1 and BRCA2 pathogenic variants cuts the long-term risk of death by…
Patients with obstructive sleep apnoea treated with a novel surgical technique have persistent long-term symptom improvements up to 3.5 years post-surgery, Australian doctors report. Although the combination upper…
In the previous edition of the Psychiatry Update newsletter, we carried an advertisement for medicinal cannabis by a company called BHC and their product CanView. The advertisement…
Obstetricians and gynaecologists are the latest specialties to confront a debate on whether being a fellow of a ‘royal’ college is outdated and offensive. Professor James Nicklin and Dr Greg Robertson…
Doctors are criticising the adoption of the term ‘obstetric violence’ in a parliamentary inquiry into the prevalence of birth trauma. Dubbed the ‘MeToo of childbirth’,…
Small colorectal polyps that grow at follow-up screening are three times more likely to have advanced histology than stable or regressing polyps, show results from…
Gastric bypass surgery is associated with an increased risk for non-alcohol substance use disorder, according to a study in Obesity. Dr Per-Arne Svensson (PhD), from…
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